Prof. Jung Ji-hoon of SKKU, Drug delivery technology Development to replace needles
- 성균융합원
- Hit2632
- 2018-09-06
Prof. Jung Ji-hoon of SKKU, Drug delivery technology Development to replace needles
Prof. Jung of the College of Pharmacy and Prof. Yong Taek Lim of the Nanotechnology Research Institute have developed a drug delivery technology that can replace needles.
Soluble super fine particles penetrate the horny layer of skin when they adhere to the skin and dissolve in a short time. The greatest advantage is that there is little pain or tissue damage during this process. However, existing technologies have been difficult to formulate active ingredients that are insoluble in water.
The researchers used the feature that the amphipathic polymer melts in water and forms nanoparticles through self-assembly. The researchers also reported that by using the phenomenon that 30 nanometer sized self-assembled nanoparticles are transferred to the lymph nodes after the attachment of the superfine fine skin, they can improve the effect of the anti-cancer vaccine by transmitting immune enhancer, which is not soluble in water, And confirmed that the response can be greatly reduced.
The research was supported by the Korea Research Foundation's Center for Advanced Research Support and ERC, and it was published on August 24th in the online edition of ACS Nano, the global authority on nanoscience.