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- Successful development of bio-catalyst for synthesis of anti-inflammatory agent
- Professor Kim Kyung-gyu of the Department of Medicine, Successful development of bio-catalyst for synthesis of anti-inflammatory agent -Enzyme activity improvement through protein engineering research based on protein structure- Professor Kim Kyung-gyu of the Department of Medicine has identified the three-dimensional structure of the protein enzyme Est-Y29 extracted from soil microorganisms. Through research on structure-based protein engineering, it is possible to produce environmentally friendly kettophen which is one of the main raw materials for external anti- The company said. The production of fine chemicals such as pharmaceuticals has been done through chemical synthesis, but some approaches require the use of environmentally friendly biocatalysts that can replace or replace hazardous substances due to economic inefficiencies. Professor Kim Kyung-kyu, "In this study, we developed a bio-catalyst that can replace chemical catalysts through a protein engineering approach based on the three-dimensional structure of proteins, and through this, we proposed the possibility of producing environmentally friendly effective drugs such as ketoprofen" He said. This research was carried out by the Rural Development Administration's next-generation Bio Green 21 project and the Korea Research Foundation. The study was published online on December 24 at ACS Catalysis, an international journal of catalysis.
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- 작성일 2018-12-31
- 조회수 2814
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- Prof. Karsten Rott's Research Team (Dept. of Physics) Participated in the IBS Dark Matter Study
- Prof. Karsten Rott's Research Team (Dept. of Physics) Participated in the IBS Dark Matter Study The Cosine-100 Collaborative Research Unit of IBS (Institute for Basic Science) which SKKU research team led by Prof. Karsten Rott (Dept. of Physics) participated paved the way for long-standing controversy surrounding dark matter signal that Dama experiment had observed. The results of this research were published at the online edition of Nature (IF 42.351) on December 6th at 3 AM. In the paper, data from the cosine-100 experiment suggested that there is insufficient evidence that the signal detected by the Dama experiment is caused by dark materials, and disproved most of the theories based on the results of the Dama experience. Currently, two graduate students of our university are participating in the cosine-100 experiment and are conducting a detector simulation. SKKU team has been participated in this experiment from the beginning of detector production and is contributing on the data monitoring from the detector. "The cosine-100 experiment will continue to collect data. We hope that we will be able to fully understand the anomalies observed by the Dama experiment, Prof. Karsten said. “Although this result does not directly identify the presence of dark matter, it may discovered a new phenomenon that we do not yet.”
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- 작성일 2018-12-18
- 조회수 2519
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- Development of optical synapse semiconductor device
- Simultaneous learning of color and form... Development of optical synapse semiconductor device The Korea Research Foundation announced on December 9 that Professor Park Jin-hong of Sungkyunkwan University and Seo Seung-hwan integrated research student team have developed optic synapse semiconductor device technology that imitates optic nerve. Nyumochipchip, which imitates the principle of human brain operation, is attracting attention as next generation information processing technology. Power consumption can be minimized while processing a large amount of information, and its own computation function can be enhanced. The team combined synaptic mimic semiconductor devices with optical semiconductor sensors to create components that exhibited different synaptic properties in different colors. The research was carried out by the Ministry of Science and Technology, the Ministry of Information and Communication, the Korea Research Foundation, the Nanomaterial Technology Development Project, and the Basic Research Project. A paper was published on November 30 in Nature Communications. article : https://www.yna.co.kr/view/AKR20181206125000063?input=kkt
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- 작성일 2018-12-11
- 조회수 2493
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- SKKU Prof. Kim Tae Sung’ Research Team, Fabrication of large-area thin-film heterogeneous structure using plasma
- SKKU Prof. Kim Tae Sung’ Research Team, Fabrication of large-area thin-film heterogeneous structure using plasma -November 15th, Publication of "Application Surface Science" (IF: 4.44)- Professor Kim Tae Sung of the Mechanical Engineering Department of the College of Engineering has developed the world's first technology for low-temperature synthesis of a large-sized MoS2-Graphene heterojunction structure. The paper was published on November 15, 2018 in the international journal "Applied Surface Science" (IF: 4.44). This project is the result of a study by the Korea Research Foundation (NRF-2017R1A2B3011222), the Presidential Postdoctoral Fellowship (NRF-2014R1A6A4A04058169), and the Individual Basic Research Support Project (NRF-2018R1D1A1B07040292) It is expected to contribute to application and commercialization of heterogeneous area. https://www.skku.edu/skku/campus/skk_comm/news.do?mode=view&articleNo=68359
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- 작성일 2018-12-04
- 조회수 2455
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- [NCIS] 1st place in private universities Sungkyunkwan University
- [NCIS] 1st place in private universities Sungkyunkwan University As a result of the National Customer Satisfaction Index (NCSI) survey in the fourth quarter of 2018, Sungkyunkwan University ranked first. Article : http://news.chosun.com/site/data/html_dir/2018/12/02/2018120200831.html
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- 작성일 2018-12-03
- 조회수 2445
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- Prof. Lee of Nanostructured Physics Research Team solved two-dimensional matter heterogeneous synthesis problem
- Prof. Lee of Nanostructured Physics Research Team solved two-dimensional matter heterogeneous synthesis problem Prof. Lee of Nanostructured Physics Research Team solved the two-dimensional heterogeneous synthesis problem through collaborative research A team of Korean researchers developed the world's first technology to synthesize boron nitride, a two-dimensional material composed of different elements, into a single crystal. Hexagonal boron nitride (hBN) is a hexagonal atomic structure like graphene, which has a plate-like structure consisting of boron and nitrogen instead of carbon. The research results were published in the November 16 issue of the world's top international scientific journal Science. The results of this study have been evaluated as suggesting a new research paradigm that can grow heterogeneous stacks of various 2D materials into large area single crystals. Based on this, it is expected to greatly revolutionize the development of next-generation transparent electronic devices, gas barrier, sensors and filters. The results of this research were carried out by the support of basic research support project (private research), basic science research institute, and Korea Institute of Science and Technology institute. http://www.edaily.co.kr/news/read?newsId=01216886619406376&mediaCodeNo=257
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- 작성일 2018-11-23
- 조회수 2499
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- Antibiotic resistance can be overcome in Angelica Utilis Makino
- Antibiotic resistance can be overcome in Angelica Utilis Makino Detecting effective substances for new anti-toxic infection treatment without resistance Prof. Kim Kyung-gyu (Department of Sungkyunkwan University School of Medicine) and Prof. Lee Seung-seo (University of Southampton, UK) have shown that Angelica Utilis Makino can inhibit the virulence of resistant Staphylococcus aureus and effectively treat infection with resistant bacteria. The researchers found that a substance called zanthoxylerol, which is made from Angelica Utilis Makino, inhibits the synthesis of virulence factors of Staphylococcus aureus, which is one of the typical resistant bacteria, and that the bacteria causing the infection are killed by immune action without causing the disease. In addition, we have found a method of synthesizing this substance by organic chemistry and synthesized various derivatives to obtain PM56, an antioxidant substance having better properties than zanthoxylerol. Prof. Kim said "By verifying the success of new antibiotics that inhibit toxicity, we can expect to develop new antibiotics without resistance." The results of the study were published as an ASAP article on November 15 in the Journal of Medicinal Chemistry in the International Journal of Medicinal Chemistry.
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- 작성일 2018-11-20
- 조회수 2239
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- 'The Age of Quantum Biology Comes' Institute Quantum of Biophysics (IQB)
- 'The Age of Quantum Biology Comes' Institute Quantum of Biophysics (IQB) In recognition of the importance of quantum biology and establishing itself as a leader in the field of quantum life science at our university, the Institute of Quantum Biophysics (IQB) was established this fall. The goal of IQB is to build a scientific foundation for the development of innovative quantum health technologies with basic science, engineering and medical researchers. SKKUZINE : https://webzine.skku.edu/skkuzine/section/coverStory.do?articleNo=67753&pager.offset=0&pagerLimit=10
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- 작성일 2018-11-19
- 조회수 2299
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- Development of a Degradation-Regulatable Architechtured Implantable Macroporous Scaffold: Dr-AIMS
- Research Stories Development of a Degradation-Regulatable Architechtured Implantable Macroporous Scaffold: Dr-AIMS The drawbacks of i.v. injection such as low targeting efficacy and varied side effects, could be resolved. Further, it can be developed as an on-demand drug delivery system based on the analysis of tumor tissues. SKKU Advanced Institute of Nano Technology Prof.LIM, YONGTAIK Researcher Ren Long Professor Yong Taik LIM`s group from SKKU Advanced Institute of Nanotechnology(SAINT) of Sungkyunkwan University has developed a degradation-regulatable architechtured implantable macroporous scaffold (Dr-AIMS) for spatiotemporal controlling immunosuppressive factors in tumor microenvironment, resulting in an enhanced efficiency for combination cancer immunotherapy. The Dr-AIMS was fabricated based on hyaluronic acid, the intrinsically existing biopolymer in human, with the ability to regulate the degradation kinetics for varied applications. With scaffold implantation after surgery, the immunosuppressive cells (MDSC: Myeloid-derived suppressor cells; TAM: Tumor-associated macrophages) related with tumor recurrence and metastasis can be controlled and the ability of DCs and T cells can be revigorated with reduced side effects of chemodrugs and immune checkpoint antibodies. By this approach, the drawbacks of i.v. injection, including low targeting efficacy and varied side effects, could be addressed. Further, it can be developed as an on-demand drug delivery system based on the analysis of tumor tissues. Published article : L. Ren, and Y. T. Lim, ‘Degradation-regulatable Architectured Implantable Macroporous Scaffold for the Spatiotemporal Modulation of Immunosuppressive Microenvironment and Enhanced Combination Cancer Immunotherapy’, Advanced Functional Materials, 201804490 (2018) .
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- 작성일 2018-11-15
- 조회수 2401
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- SKKU, The comprehensive evaluation of the specialization business achieved the best result ever
- SKKU, The comprehensive evaluation of the specialization business achieved the best result ever In the comprehensive evaluation of the university specialization project (CK-Ⅱ) supervised by the Ministry of Education and the Korea Research Foundation, three of the six project teams achieved the highest achievement in receiving the A grade. The Creative Informatics Talent Development Team (Leader Shin Dong-ryul, hereinafter referred to as the large project team) received the highest grade among the five projects in the university's autonomous non-engineering (mass-type) sector in Seoul for three consecutive years. Our university has been running a specialization project for the fifth year since the 2014 school year and has received about 4 billion won of government subsidy each year. The detailed results of this comprehensive evaluation are as follows.
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- 작성일 2018-11-14
- 조회수 2877